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Departamento de Santa Cruz Hotels for Your Next Holiday

Why Tourists Visit Departamento de Santa Cruz

• Visit the UNESCO World Heritage Jesuit Missions in Chiquitos.
• Explore Amboró National Park’s lush trails and diverse wildlife.
• Sandboard down the impressive dunes of Lomas de Arena.
• Enjoy vibrant nightlife and upscale dining in Santa Cruz de la Sierra.
• Shop for handmade crafts and textiles at local artisan markets.

Santa Cruz offers over 180 hotel options, including everything from luxurious 5-star properties like Marriott Santa Cruz (starting at $140 per night) to budget-friendly 3-star options such as Hotel LP Santa Cruz (averaging around $40 per night). The city center and Equipetrol neighborhood house most hotels, with newer additions like Swissotel Santa Cruz standing out for its modern amenities and rooftop pool.

Departamento de Santa Cruz is Bolivia's largest and most economically dynamic region, known for its tropical climate, diverse ecosystems, and bustling city life centered around Santa Cruz de la Sierra.

Key attractions like the Jesuit Missions of Chiquitos, Amboró National Park, and Lomas de Arena ensure there’s something for adventure seekers, history lovers, and nature enthusiasts.

The region draws visitors with its unique mix of modern urban experiences and stunning natural beauty, complemented by an array of cultural landmarks and Amazonian biodiversity.

Departamento de Santa Cruz Tips You Must Know

• Book hotels 1-2 months in advance for the best prices, especially during the dry season (May to October).

• Choose hotels near the city center to minimize transportation hassles and stay close to top attractions.

• Public buses are inexpensive but slow—consider using affordable ride-share apps like InDriver for convenience.

• Pack lightweight, breathable clothing and plenty of insect repellent for outdoor adventures.

• Always confirm if your hotel provides airport transfers to avoid last-minute transportation stress.

Santa Cruz de la Sierra

Santa Cruz de la Sierra, the vibrant capital, impresses with Plaza 24 de Septiembre, a bustling hub surrounded by colonial architecture and cafes. The city boasts the Guembe Biopark & Resort, a haven for wildlife and butterfly enthusiasts. Its Equipetrol neighborhood offers diverse dining options and a thriving nightlife that's hard to resist.

Explore the variety of hotels in Santa Cruz de la Sierra to enhance your stay in Bolivia's bustling capital.

San Ignacio de Velasco

San Ignacio de Velasco hosts the iconic Jesuit Mission, a UNESCO World Heritage site showcasing exquisite Baroque-style wooden churches. This serene city offers lagoons and beautiful landscapes perfect for a tranquil escape. Visitors often discover the annual music festivals highlighting sacred Baroque ensembles.

Discover charming hotels in San Ignacio de Velasco while exploring Bolivia's historic Jesuit heritage.

Samaipata

Samaipata, nestled in the Andes foothills, features the archaeological wonder of El Fuerte, a pre-Columbian UNESCO World Heritage site. The nearby Amboró National Park offers unmatched biodiversity for nature lovers. Samaipata's wineries and quaint cafes add a touch of charm to this small mountain town.

Unwind at cozy hotels in Samaipata, a perfect base for history and nature enthusiasts.

Roboré

Roboré, known as the 'Land of Thermal Waters,' captivates with natural hot springs like Aguas Calientes. The Santiago de Chiquitos mission is a mix of history and scenic views. Nearby Chochís Sanctuary surprises visitors with its stunning cliffside architecture and peaceful ambiance.

Soak in relaxation and book your next stay at exceptional hotels in Roboré.

Concepción

Concepción, a small town with big cultural significance, houses one of Bolivia’s most beautifully restored Jesuit Missions. The town is alive with traditional crafts, particularly wood carving. Lake Concepción offers opportunities for boating and birdwatching amidst tranquil scenery.

Find welcoming hotels in Concepción while uncovering local Jesuit history and natural beauty.

Central Hotels that Keep You Close to the Action

Find more comfortable and accessible Central hotels in Santa Cruz de la Sierra.

Hotel Name

Description

Price per night

La Siesta Hotel

City center

Plaza 24 de Septiembre (0.7 km)
Catedral Metropolitana (0.8 km)
Arenal Park (1 km)

Known for its lush central courtyard, it's a hidden oasis in the city's bustling heart. The hotel has been a favorite for travelers exploring Santa Cruz's historic neighborhoods.

Great service
Beautiful courtyard garden
Close to landmarks

$30-$50/night

Cosmopolitano Hotel Boutique

City center

Catedral Metropolitana (0.9 km)
Casa de la Cultura (1 km)
La Recova Market (0.5 km)

A restored colonial house turned into a chic boutique property, offering a rooftop pool with remarkable city views. The decor is inspired by Bolivian art and culture for a true local experience.

Stylish decor
Rooftop pool
Central location

$80-$100/night

Hotel Camino Real

Equipetrol

Ventura Mall (1.1 km)
Plaza 24 de Septiembre (4.5 km)
Zoo Fauna Sudamericana (2.5 km)

This central pick offers a lagoon-esque outdoor pool surrounded by palm trees. It is one of few hotels in the area with a spa offering traditional Bolivian-style treatments.

Luxurious amenities
Spa services
Resort-style pool

$100-$150/night

Luxury Hotels for the Ultimate Stay

Discover more sophisticated Luxury hotels in Santa Cruz de la Sierra for a memorable stay.

Hotel Name

Description

Price per night

Chairu Eco Hotel

Equipetrol

Ventura Mall (0.9 km)
Hard Rock Cafe Santa Cruz (1.1 km)
Cine Center (3 km)

This eco-conscious gem is built with sustainable materials, incorporating solar energy and rainwater harvesting systems. Guests love its outdoor yoga area overlooking lush vegetation.

Sustainable practices
Serene atmosphere
Unique yoga facilities

$150-$200/night

Sun Hotel

Viru Viru Airport area

Viru Viru International Airport (1.5 km)
Santa Cruz Zoo (8 km)
Plaza 24 de Septiembre (12 km)

Located near the airport, this luxury option blends convenience with indulgence, featuring Bolivia's only heated outdoor pool with underwater lighting. Its buffet brunches are famous among travelers.

Airport proximity
Heated outdoor pool
Renowned buffet

$120-$170/night

Los Tajibos, Santa Cruz De La Sierra, A Tribute Portfolio Hotel

Equipetrol

Ventura Mall (0.8 km)
Plaza 24 de Septiembre (4.6 km)
Santa Cruz Cultural Center (2.5 km)

This iconic property has hosted top international artists performing in Santa Cruz. Its sprawling grounds include an outdoor pool reminiscent of tropical resorts.

Celebrity history
Resort-like amenities
Prime location

$180-$250/night

Boutique Hotels with Unique Character

Explore more cozy Boutique hotels in Santa Cruz de la Sierra with distinct charm.

Hotel Name

Description

Price per night

Senses Hotel Boutique Plaza

City center

Plaza 24 de Septiembre (0.2 km)
Catedral Metropolitana (0.3 km)
Sacred Art Museum (0.4 km)

Located right off the main square, this hotel provides rooftop dining with views of the Santa Cruz Cathedral. Every room is uniquely designed with modern art pieces.

Artistic design
Central location
Gourmet rooftop restaurant

$90-$120/night

Alfonsina Hotel Boutique

Sirenes District

Ventura Mall (2 km)
Casa de la Cultura (3.5 km)
Plaza Blacutt (3 km)

Tucked away in a quiet neighborhood, it features quirky European-inspired decor and a small library with rare Bolivian books. The cozy garden café is a favorite for visitors.

Peaceful ambiance
Quaint café
Eclectic design

$110-$130/night

Hotel Senses Centro

City center

Plaza 24 de Septiembre (0.3 km)
Catedral Metropolitana (0.4 km)
La Recova Market (0.5 km)

One of the few boutique properties offering a rooftop infinity pool, ideal for sunset gazing. The hotel incorporates subtle nods to local textile designs in its interiors.

Infinity pool
Locally inspired decor
Prime downtown spot

$100-$140/night

Family-Friendly Hotels with Comfort for All

Check out more charming Family Friendly hotels in Santa Cruz de la Sierra for your family holiday.

Hotel Name

Description

Price per night

Hotel Plaza Center

City center

Arenal Park (0.8 km)
Catedral Metropolitana (0.7 km)
Plaza 24 de Septiembre (0.6 km)

Offering spacious family suites, this hotel has a supervised kids’ playroom, giving parents a much-needed break. Located centrally, it's a great base to explore Santa Cruz’s attractions.

Family suites
Kids' playroom
Central location

$50-$80/night

Yvy Casa Hotel

Equipetrol

Ventura Mall (1.5 km)
Arenal Park (3.5 km)
Zoo Fauna Sudamericana (2.7 km)

With a garden featuring native plants, this eco-friendly family hotel teaches kids about Bolivian flora and fauna. They provide family picnics as part of their weekend packages.

Eco-friendly design
Family activities
Tranquil garden

$70-$100/night

Buganvillas Hotel Suites

Urubo District

Plaza 24 de Septiembre (5 km)
Ventura Mall (6 km)
Amboró National Park Entrance (40 km)

This resort-style property offers kid-friendly pools and on-site tennis courts, perfect for active families. The large suites make extended family stays more comfortable.

Resort amenities
Large suites
Tennis courts

$120-$180/night

Hotels With Indoor Pools for a Relaxing Stay

Find other restful Hotels with indoor pool in Santa Cruz where you can enjoy a relaxing swim.

Hotel Name

Description

Price per night

Departamentos En Edificio Acrebol Santa Cruz

City center

Cine Center (1 km)
Casa de la Cultura (1.2 km)
Plaza 24 de Septiembre (1.5 km)

This apartment-style hotel has a sleek indoor pool with natural lighting through glass panels. It’s a perfect option for travelers seeking self-contained accommodations near downtown.

Modern design
Great downtown location
Self-contained units

$60-$90/night

Apartamento Moderno En Equipetrol, Con Cine - Piscina - Gym Y Parqueo Gratuito. Proximo A Los Tajibos, Ventura Mall, Super Icenorte

Equipetrol

Ventura Mall (0.7 km)
Hard Rock Cafe Santa Cruz (0.9 km)
Cine Center (3 km)

Blending unique amenities like a private mini-cinema, this property features both an indoor pool and gym. It’s a top pick for modern travelers who enjoy entertainment at home.

Private cinema
Modern amenities
Spacious design

$80-$120/night

Apartamento Moderno, Delicado Y Confortable

Los Cusis

Zoo Fauna Sudamericana (1.8 km)
Ventura Mall (2.3 km)
Plaza 24 de Septiembre (4.5 km)

This cozy apartment offers an exclusively reserved indoor pool for guests, perfect for private swims. It's designed with comforting minimalist aesthetics and soft lighting.

Minimalist design
Private pool access
Peaceful environment

$70-$110/night

Frequently asked question

What are the best hotels near Plaza 24 de Septiembre?

Several hotels, like Senses Boutique Hotel and Casa Patio Hotel Boutique, are within walking distance of Plaza 24 de Septiembre, offering easy access to Santa Cruz's main square and key attractions.

Are there family-friendly hotels in Departamento de Santa Cruz?

Yes, family-friendly hotels like Marriott Santa Cruz de la Sierra Hotel and Radisson Hotel Santa Cruz provide kid-friendly amenities such as pools and spacious family suites.

What is the typical cost of a mid-range hotel in Santa Cruz de la Sierra?

The cost of mid-range hotels in Santa Cruz de la Sierra generally ranges from $50 to $100 USD per night, with options including complimentary breakfast and Wi-Fi.

Are there boutique hotels in Santa Cruz for couples looking for a romantic stay?

Yes, boutique hotels such as Hotel Boutique Ines Maria offer intimate settings, charming decor, and personalized services ideal for couples.

Do hotels in Santa Cruz provide airport transportation?

Many hotels, including Camino Real Hotel and Los Tajibos Hotel, offer airport shuttle services, often for an additional fee or included in premium packages.